Schedule a free initial consultation with our IVF specialist. You can have the consultation online from the comfort of your home
or meet with us in person at our clinic, depending on your preferences.

During the consultation, our experienced IVF specialist will explain the entire process of IVF treatment with donor eggs.
You will discuss your and your partner's medical history, focusing primarily on your reproductive health.

In order to eliminate potential health risks for the future parents and their baby, partners must undergo a series of medical tests. These include basic gynaecological examinations, semen analysis, and blood tests for both partners. Similarly, the egg donor undergoes a series of detailed medical examinations including genetic testing. Detailed medical tests help us protect the health of both the patient and the egg donor.

You can undergo these examinations either at our clinic or in your own country. If you choose the latter, your coordinator will send you all necessary documents for the health tests electronically.

GENNET's doctor will then request the test results necessary for the treatment. They may also recommend additional examinations to help improve the treatment success. You can send us the results via email, and then you will only need to come to Prague for the final part of the treatment, approximately 5-7 days.
 
Based on the results of all examinations, the doctor will establish a comprehensive treatment plan and recommend suitable laboratory methods to maximise the chances of successful pregnancy.

Donation of gametes in the Czech Republic is voluntary, completely anonymous, and non-commercial (donors are compensated for expenses related to the donation process - medications and vitamins, transportation, accommodation if needed, lost wages). Patients only learn basic non-identifying characteristics about the donor. From our extensive database, we select a donor based on the physical characteristics of the couple, including blood type and phenotype (eye colour, hair colour, height, weight, skin colour, ethnicity).

All our donors must undergo a series of detailed medical examinations including genetic testing.

The doctor will plan the treatment to synchronise the menstrual cycles of the patient and the donor so that both women are prepared for egg retrieval and subsequent embryo transfer at the right time.

At GENNET, we have strict criteria for egg donors, and each donor must undergo a series of detailed health tests.

The medical screening of a donor typically includes the following tests:

• Complete blood count,
• Hormone tests for AMH and TSH,
• Blood type and Rh factor,
• Tests for infectious diseases and sexually transmitted infections (HIV, hepatitis B and C, syphilis),
• Drug and substance abuse screening,
• Routine gynaecological examination including ultrasound.

During the genetic consultation, the potential egg donor discusses with a geneticist the history of diseases present in her family, the ethnic background of her extended family, and other significant hereditary predispositions.

This meeting is focused on genetics and provides us with another opportunity to get to know the potential donor and ensure the highest chance for patients to have a healthy baby.
As part of this genetic testing, the donor undergoes:

• Karyotype analysis: assessment of chromosome structure and number,
• Genetic tests for commonly occurring genetic diseases in the population:
  • Cystic fibrosis,
  • Spinal muscular atrophy,
  • Deafness,
  • Sex-linked genetic disorders.

We synchronise the menstrual cycles of both the patient and the donor using contraception (or alternatively, Norethisterone). Subsequently, the donor undergoes hormonal stimulation to mature a larger quantity of eggs than in a natural cycle. Hormonal stimulation typically lasts about 14 days.

At the onset of her menstrual cycle, the patient also begins preparation for embryo transfer. Based on a tailored stimulation protocol, she takes medications aimed at optimally preparing the uterine lining for embryo implantation. During this preparation phase, the proper growth of the lining is monitored through 1-2 ultrasound examinations.

Approximately 14 days after hormonal stimulation, when the follicles have reached optimal size for retrieval, the donor undergoes egg retrieval. The procedure is conducted under ultrasound guidance using a special thin needle inserted through the vaginal vault to the ovaries. The donor is under short general anaesthesia during the procedure.

On the day of egg retrieval, the patient's partner provides a semen sample. Alternatively, previously frozen sperm samples can be used for egg fertilisation.

The eggs retrieved are subsequently fertilised with the patient's partner's sperm under laboratory conditions. At GENNET, we typically use the ICSI method for egg fertilisation.

Additionally, at this stage of treatment, based on recommendations from the doctor, embryologist, or patient preferences, other laboratory methods may be employed to increase the chances of successful treatment:

• ICSI - intracytoplasmic sperm injection directly into the egg (part of the IVF treatment package with donated eggs)
• MFSS method - for selecting the highest quality sperm
• Extended cultivation - method for selecting the highest quality embryos (part of the IVF treatment package with donated eggs)
• Continuous embryo monitoring - ensures optimal conditions for embryo development with continuous monitoring

After 5 days of embryo cultivation, the embryologist selects the embryo with the highest potential for successful implantation in the uterus and subsequent healthy pregnancy.
The quality of the embryo is determined by:

• Egg quality
• Sperm quality
• Combination of genetic information from both partners

Due to the high effectiveness of assisted reproduction methods, treatment success, and efforts to minimise risks associated with multiple pregnancies, typically only one embryo (in exceptional cases, two embryos) is transferred into the patient's uterus.

The embryo transfer procedure is painless, performed without anaesthesia, under ultrasound guidance, and the patient can typically leave the clinic about 15 minutes after the procedure.

If multiple promising embryos are obtained during the treatment cycle, they can be preserved for future use through vitrification (freezing).

Selection of the suitable embryo for transfer can also be assisted by preimplantation genetic testing. In this case, the embryo undergoes genetic testing before transfer to the uterus. We offer three methods for such genetic testing of embryos:

• PGT-M/SR
• PGT-A

All embryos undergo preimplantation genetic testing at the blastocyst stage (approximately 5-day-old embryos after extended cultivation). After sample collection, the embryo is frozen. The results of the testing process take about 30 days. Upon receiving the results, the patient begins preparation for the transfer of a healthy embryo in a new cycle. In the case of frozen embryo transfer, the patient typically visits Prague for only 2-3 days.

Approximately 14 days after embryo transfer, the patient undergoes a blood test to measure hCG levels. This hormone level determines if the patient is pregnant. Within the following two to three weeks, the patient undergoes an ultrasound examination to confirm foetal heart activity. Medication is typically continued until the 12th week of pregnancy.